function and mutations. The focus of Phyre2 is to provide biologists with a simple and intuitive interface to state-of-the-art protein bioinformatics tools. Phyre2 replaces Phyre, the original version of the server for which we previously published a paper inNature Protocols. In this updated...
The Phyre2 server may be used in several different ways depending on the focus of the user's research. The most commonly used facility is the prediction of the 3D structure of a single submitted protein sequence. Advanced facilities include: (i) Backphyre, to search a structure against a ...
Fold Recognition by the 3D-PSSM server () === Summary Fold Recognition Results (For Alignments see Below) === Results are sorted by E-value, most confident assignment first. E-values below 0.05 are highly confident. E-values up to 1.0 are worthy of attention. Often the top ranking hit ...
Kelley, L.A. & Sternberg, M.J.E. Protein structure prediction on the web: a case study using the Phyre server.Nat. Protoc.4, 363–371 (2009). Mao, C. et al. Functional assignment ofMycobacterium tuberculosisproteome by genome-scale fold-recognition.Tuberculosis1, 93 (2013). ...